Tesamorelin 20MG

$94.86

Category: Cellular Aging Research

Description
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Tesamorelin Research Peptide

Tesamorelin is a synthetic peptide analog of human growth hormone–releasing hormone (GHRH), used in scientific studies to investigate its effects on hormone regulation and metabolism.

Tesamorelin (Research Use Only)

Chemical Name: Tesamorelin acetate

Synonyms: TH9507, Egrifta, Egrifta SV

CAS Number: 218949-48-5

Sequence: Tyr–Ala–Asp–Ala–Ile–Phe–Thr–Asn–Ser–Tyr–Arg–Lys–Val–Leu–Gly–Gln–Leu–Ser–Ala–Arg–Lys–Leu–Leu–Gln–Asp–Ile–Met–Ser–Arg–Gln–Gln–Gly–Glu–Ser–Asn–Gln–Glu–Arg–Gly–Ala–Arg–Ala–Arg–Leu–NH₂

Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S

Molecular Weight: 5135.86 g/mol (free base)

Molecular Weight (acetate form): ≈5579 g/mol

Description

Tesamorelin is a synthetic analog of growth hormone–releasing hormone (GHRH) designed to stimulate natural growth hormone (GH) secretion and elevate insulin-like growth factor 1 (IGF-1) levels. This peptide is frequently studied for its effects on visceral adipose tissue (VAT) reduction and lipid metabolism, particularly in models involving HIV-associated lipodystrophy.

Research Applications

Investigated for body composition modulation and targeted lipolytic action.
Studied in metabolic and endocrine research related to GH and IGF-1 activity.
Demonstrated reduction in visceral and liver fat without adverse glucose metabolism effects.
52-week studies show sustained VAT reduction (~18%) and improved lipid levels.

Key Research & Reports

Mechanism of Action

Tesamorelin binds to the pituitary GHRH receptor, enhancing the pulsatile release of GH. The increased GH then promotes hepatic IGF-1 synthesis, initiating anabolic and lipolytic pathways that improve body composition and fat metabolism profile in research subjects.

Safety and Handling

Tesamorelin demonstrates a strong safety profile in controlled research settings. Reported transient effects include localized injection site reactions and temporary fluid retention. Store lyophilized vials at −20°C. Reconstitute only prior to laboratory use.

Disclaimer

For laboratory research use only. Not for human consumption, medical treatment, or veterinary applications. All data provided is for educational and informational purposes specific to research contexts.