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Home / Individual Peptides Research

Semax

$43.86

Category: Individual Peptides Research
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Semax (Research Use Only)

Chemical Name: Semax (ACTH 4-10 analog)

CAS Number:
80714-61-0

Molecular Formula: C37H51N9O10S

Molecular Weight: 813.92 g/mol

Sequence: Met-Glu-His-Phe-Pro-Gly-Pro

Appearance: White to off-white powder

Storage: Store at 2–8°C, protect from light and moisture

Form: Lyophilized powder; soluble in water or DMSO


Description

Semax is a synthetic heptapeptide analogue of the ACTH (4-10) fragment with nootropic, neuroprotective, and anxiolytic properties. It modulates the expression of neurotrophins and supports neuronal survival under stress conditions such as hypoxia and glutamate toxicity. Semax is studied for its potential to improve cognitive functions, neuroplasticity, and brain circulation in various research models.
(Wikipedia)
(PubChem)


Research Applications

  • Nootropic and cognitive enhancement studies
  • Neuroprotection and stroke recovery research
  • Investigation of neurotrophic factor modulation
  • Anxiolytic and stress response modulation
  • Brain circulation and plasticity improvement

Key References

  • Semax Neuroprotective Mechanisms – PMC
  • Clinical Evaluation of Melanocortin Peptides – PubMed
  • Sigma-Aldrich Semax Product Information
  • ChemicalBook Specifications for Semax

Mechanism of Action

Semax modulates the expression of brain-derived neurotrophic factor (BDNF) and other growth factors that enhance neuronal survival, plasticity, and cognitive function. It also acts as an antioxidant and anti-inflammatory agent in neural tissues.


Safety and Handling

Store lyophilized Semax powder at 2–8°C. Prepare solutions immediately prior to research use under sterile conditions. Demonstrates a favorable safety profile with minimal adverse effects reported in animal and human research.


Disclaimer

For laboratory research use only. Not intended for human, veterinary, medical, or diagnostic applications. Provided for scientific and educational research purposes only.

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