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Epithalon 40mg

$61.20

Category: Cellular Aging Research

Description
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Epithalon (Epitalon) (Research Use Only)

Chemical Name: Epithalon (Ala-Glu-Asp-Gly)

CAS Number:
307297-39-8

Molecular Formula: C₁₄H₂₂N₄O₉

Molecular Weight: 390.35 g/mol

Sequence: Ala-Glu-Asp-Gly

Appearance: White to off-white powder

Storage: Store lyophilized powder at −20°C, protect from moisture and light

Form: Lyophilized peptide powder, soluble in DMSO or water

Description

Epithalon (also known as Epitalon) is a synthetic tetrapeptide derived from a naturally occurring polypeptide produced in the pineal gland. It is widely researched for its potential anti-aging, geroprotective, and telomerase-activating properties. Epithalon has demonstrated capabilities in regulating circadian and hormonal rhythms, promoting telomere elongation, reducing oxidative stress, and supporting DNA repair mechanisms.
(Wikipedia)
(PubChem)

Research Applications

Telomerase activation and telomere length regulation studies
Anti-aging and longevity research
Epigenetic regulation and chromatin remodeling
Oxidative stress reduction and antioxidant gene expression
Neuroendocrine modulation and melatonin synthesis support
Wound healing and fibrotic programming investigations

Key References

Mechanism of Action

Epithalon stimulates telomerase activity leading to telomere elongation and cellular lifespan extension in vitro. It influences melatonin synthesis regulation, antioxidant gene expression (SOD2, CAT, HMOX1), and modulates epigenetic marks affecting genome stability, potentially reducing cellular senescence and promoting regenerative phenotypes.

Safety and Handling

Store Epithalon lyophilized powder at −20°C protected from moisture. Reconstitute immediately before research use. Experimental studies report minimal toxicity and favorable safety profiles in preclinical models.

Disclaimer

For laboratory research use only. Not for human, veterinary, medical, or diagnostic application. All information is provided for research and educational purposes.