Mots C – 40mg

$64.26

Categories: Cellular Aging Research, Individual Peptides Research

Description
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MOTS-C (Research Use Only)

Chemical Name: MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)

CAS Number:
1627580-64-6

Molecular Formula:
C₁₀₁H₁₅₂N₂₈O₂₂S₂

Molecular Weight: 2174.6 g/mol

Sequence: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH

Appearance: White to off-white lyophilized powder

Storage: Store at −20°C for long-term stability

Form: Lyophilized solid; soluble in water or DMSO

Description

MOTS-c is a 16-amino acid mitochondrial-derived peptide that plays a key role in regulating cellular metabolism, energy homeostasis, and stress response. It is involved in promoting metabolic flexibility by activating AMP-activated protein kinase (AMPK), enhancing glucose metabolism and improving insulin sensitivity. MOTS-c has been shown in research to support mitochondrial function, metabolic health, and longevity.
(Wikipedia)
(PubChem)

Research Applications

Metabolic regulation and improvement of insulin sensitivity
Studies on mitochondrial function and cellular energy homeostasis
Investigation of anti-inflammatory and anti-aging effects
Bone metabolism and support for osteoporosis models
Potential protective effects against metabolic and inflammatory diseases

Key Research & Reports

Mechanism of Action

MOTS-c activates AMP-activated protein kinase (AMPK), a key regulator of cellular energy balance. This activation promotes increased glucose uptake and utilization, enhanced lipid metabolism, and reduced inflammation, thereby improving metabolic health and resilience to stress at the cellular level.
(Selleck Chemicals)

Safety and Handling

Store lyophilized MOTS-c peptide at −20°C to maintain stability. Reconstitute in sterile water or DMSO immediately before use. Limited reports describe mild injection site irritation; overall, MOTS-c demonstrates a favorable safety profile in research studies.

Disclaimer

For laboratory research use only. Not for human consumption, medical, veterinary, or diagnostic use. Provided information is for academic and research purposes.